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Sanford (SFB) to Des Moines (DSM) Flights from ₹6,787

Fares on this route currently start from ₹6,787. Compare live SFB to DSM prices, non-stop and connecting flights, departure times and airline choices before booking. Use the search panel to change origin, destination, passengers, cabin and trip type instantly.
SFB → DSM Approx. 1809.21 km 04 Jun 2026 Live inventory
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Showing 25 of 90 live flights
Allegiant Air
G4-2879
06:45
06/04/2026
SFB
Orlando Sanford International Airport
1h 52m
Non-stop
08:37
06/04/2026
DSM
Des Moines International Airport
₹6,787
per person
✕ Non-refundable🔥 Last 1 seats
Delta Air Lines
DL-2080
07:00
06/04/2026
MCO
Orlando Sanford International Airport
4h 8m
1 Stop
⏱ ATL · 1h 9mATL Airport
11:08
06/04/2026
DSM
Des Moines International Airport
₹19,098
per person
✕ Non-refundable5 fare options
Delta Air Lines
DL-1742
18:15
06/04/2026
MCO
Orlando Sanford International Airport
4h 17m
1 Stop
⏱ ATL · 1h 12mATL Airport
22:32
06/04/2026
DSM
Des Moines International Airport
₹19,098
per person
✕ Non-refundable5 fare options
Delta Air Lines
DL-1505
09:00
06/04/2026
MCO
Orlando Sanford International Airport
4h 37m
1 Stop
⏱ ATL · 1h 47mATL Airport
13:37
06/04/2026
DSM
Des Moines International Airport
₹19,098
per person
✕ Non-refundable4 fare options
American Airlines
AA-609
09:00
06/04/2026
MCO
Orlando Sanford International Airport
3h 52m
1 Stop
⏱ CLT · 0h 31mCLT Airport
12:52
06/04/2026
DSM
Des Moines International Airport
₹23,349
per person
✕ Non-refundable13 fare options
American Airlines
AA-1525
08:00
06/04/2026
MCO
Orlando Sanford International Airport
4h 52m
1 Stop
⏱ CLT · 1h 32mCLT Airport
12:52
06/04/2026
DSM
Des Moines International Airport
₹23,349
per person
✕ Non-refundable13 fare options
American Airlines
AA-461
06:15
06/04/2026
MCO
Orlando Sanford International Airport
6h 37m
1 Stop
⏱ CLT · 3h 22mCLT Airport
12:52
06/04/2026
DSM
Des Moines International Airport
₹23,349
per person
✕ Non-refundable9 fare options
American Airlines
AA-810
15:51
06/04/2026
MCO
Orlando Sanford International Airport
6h 7m
1 Stop
⏱ PHL · 1h 23mPHL Airport
21:58
06/04/2026
DSM
Des Moines International Airport
₹23,349
per person
✕ Non-refundable13 fare options
American Airlines
AA-2745
06:51
06/04/2026
MCO
Orlando Sanford International Airport
8h 0m
1 Stop
⏱ DCA · 3h 44mDCA Airport
14:51
06/04/2026
DSM
Des Moines International Airport
₹23,349
per person
✕ Non-refundable13 fare options
American Airlines
AA-2100
19:32
06/04/2026
MCO
Orlando Sanford International Airport
4h 40m
1 Stop
⏱ CLT · 1h 14mCLT Airport
00:12
06/05/2026
+1
DSM
Des Moines International Airport
₹23,349
per person
✕ Non-refundable12 fare options
American Airlines
AA-2117
19:22
06/04/2026
MCO
Orlando Sanford International Airport
4h 36m
1 Stop
⏱ DFW · 0h 41mDFW Airport
23:58
06/04/2026
DSM
Des Moines International Airport
₹23,349
per person
✕ Non-refundable12 fare options
American Airlines
AA-2385
18:33
06/04/2026
MCO
Orlando Sanford International Airport
5h 25m
1 Stop
⏱ DFW · 1h 31mDFW Airport
23:58
06/04/2026
DSM
Des Moines International Airport
₹23,349
per person
✕ Non-refundable8 fare options
American Airlines
AA-2075
09:30
06/04/2026
MCO
Orlando Sanford International Airport
6h 33m
1 Stop
⏱ DFW · 2h 41mDFW Airport
16:03
06/04/2026
DSM
Des Moines International Airport
₹23,349
per person
✕ Non-refundable12 fare options
United Airlines
UA-2475
12:45
06/04/2026
MCO
Orlando Sanford International Airport
5h 24m
1 Stop
⏱ ORD · 1h 49mORD Airport
18:09
06/04/2026
DSM
Des Moines International Airport
₹23,478
per person
✓ Refundable5 fare options
United Airlines
UA-2475
12:45
06/04/2026
MCO
Orlando Sanford International Airport
6h 40m
1 Stop
⏱ ORD · 3h 3mORD Airport
19:25
06/04/2026
DSM
Des Moines International Airport
₹23,478
per person
✓ Refundable5 fare options
American Airlines
AA-2082
17:39
06/04/2026
MCO
Orlando Sanford International Airport
6h 33m
1 Stop
⏱ CLT · 3h 0mCLT Airport
00:12
06/05/2026
+1
DSM
Des Moines International Airport
₹23,478
per person
✕ Non-refundable8 fare options
American Airlines
AA-2172
08:11
06/04/2026
MCO
Orlando Sanford International Airport
7h 52m
1 Stop
⏱ DFW · 3h 56mDFW Airport
16:03
06/04/2026
DSM
Des Moines International Airport
₹23,478
per person
✕ Non-refundable8 fare options
American Airlines
AA-1228
06:30
06/04/2026
MCO
Orlando Sanford International Airport
6h 33m
1 Stop
⏱ PHL · 1h 46mPHL Airport
13:03
06/04/2026
DSM
Des Moines International Airport
₹23,478
per person
✕ Non-refundable8 fare options
American Airlines
AA-2328
14:20
06/04/2026
MCO
Orlando Sanford International Airport
7h 38m
1 Stop
⏱ PHL · 2h 54mPHL Airport
21:58
06/04/2026
DSM
Des Moines International Airport
₹23,478
per person
✕ Non-refundable8 fare options
American Airlines
AA-2097
16:57
06/04/2026
MCO
Orlando Sanford International Airport
7h 1m
1 Stop
⏱ DFW · 3h 1mDFW Airport
23:58
06/04/2026
DSM
Des Moines International Airport
₹23,478
per person
✕ Non-refundable4 fare options
Southwest Airlines
WN-2628
06:20
06/04/2026
MCO
Orlando Sanford International Airport
6h 30m
1 Stop
⏱ DEN · 1h 50mDEN Airport
12:50
06/04/2026
DSM
Des Moines International Airport
₹24,037
per person
✓ Refundable8 fare options
American Airlines
AA-938
06:30
06/04/2026
MCO
Orlando Sanford International Airport
6h 51m
1 Stop
⏱ ORD · 3h 6mORD Airport
13:21
06/04/2026
DSM
Des Moines International Airport
₹25,333
per person
✕ Non-refundable🔥 Last 5 seats12 fare options
Delta Air Lines
DL-2280
11:19
06/04/2026
MCO
Orlando Sanford International Airport
5h 47m
1 Stop
⏱ MSP · 2h 6mMSP Airport
17:06
06/04/2026
DSM
Des Moines International Airport
₹25,429
per person
✕ Non-refundable
Southwest Airlines
WN-2660
19:35
06/04/2026
MCO
Orlando Sanford International Airport
3h 55m
1 Stop
⏱ MDW · 0h 40mMDW Airport
23:30
06/04/2026
DSM
Des Moines International Airport
₹26,026
per person
✕ Non-refundable🔥 Last 2 seats13 fare options
Southwest Airlines
WN-2654
07:25
06/04/2026
MCO
Orlando Sanford International Airport
4h 5m
1 Stop
⏱ MDW · 0h 55mMDW Airport
11:30
06/04/2026
DSM
Des Moines International Airport
₹26,026
per person
✕ Non-refundable13 fare options
😕 No flights match your filters.
Sanford (SFB)
📍 Orlando Sanford International Airport
🌍 United States
🕐 GMT -5
📐 Latitude: 28.777599334716797
📐 Longitude: -81.23750305175781
Des Moines (DSM)
📍 Des Moines International Airport
🌍 United States
🕐 GMT -6
📐 Latitude: 41.534000396728516
📐 Longitude: -93.66310119628906

✈ Distance: Sanford,United States to Des Moines,USA — 1809.21 km

📅 Results on this page are loaded for 04 Jun 2026. Click View all flights for the complete live search.

Sanford to Des Moines — what to expect when booking

The SFB–DSM route is served by multiple carriers throughout the year. Fares on this route can move quickly — a price available now may not be there 30 minutes later.

If your dates are flexible, try shifting your departure by a day or two using the date strip above. Mid-week departures often show lower base fares compared to weekend starts on many routes.

The distance between Sanford,United States and Des Moines,USA is approximately 1809.21 km.

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More flights from Sanford (SFB)
48 routes
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SFB → MIA
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Sanford → Newport News
SFB → PHF
Sanford → Niagara Falls International
SFB → IAG
Sanford → Oklahoma City
SFB → OKC
Sanford → Owensboro
SFB → OWB
Sanford → Plattsburgh
SFB → PBG
Sanford → Portsmouth
SFB → PSM
Sanford → Reykjavik
SFB → KEF
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SFB → ROA
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SFB → RFD
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More flights from Des Moines (DSM)
15 routes
Des Moines → Atlanta
DSM → ATL
Des Moines → Charlotte
DSM → CLT
Des Moines → Chicago
DSM → ORD
Des Moines → Denver
DSM → DEN
Des Moines → Detroit
DSM → DTW
Des Moines → Fort Worth
DSM → DFW
Des Moines → Houston
DSM → IAH
Des Moines → Las Vegas
DSM → LAS
Des Moines → Minneapolis
DSM → MSP
Des Moines → New York
DSM → LGA
Des Moines → Phoenix
DSM → PHX
Des Moines → Punta Gorda
DSM → PGD
Des Moines → Sanford
DSM → SFB
Des Moines → St. Petersburg
DSM → PIE
Des Moines → Washington DC
DSM → DCA
❓ Frequently asked questions — Sanford to Des Moines flights

Generally yes — fares on most routes are most competitive around 4–6 weeks before departure. Booking earlier usually means better availability and a lower base fare when your dates are fixed.

The straight-line distance between Sanford,United States (SFB) and Des Moines,USA (DSM) is approximately 1809.21 km. Actual flying distance may vary slightly depending on routing.

Non-stop availability on this route varies by airline schedule and season. Use the filters below to quickly check whether direct options are available on your selected date.

Mid-week departures often show lower prices than weekend travel on many routes. Use the date strip above to compare nearby days quickly.